GH secretagogue
CJC-1295 without DAC (Mod GRF 1-29)
Tetra-substituted GHRH (1-29) with no Drug Affinity Complex, so it clears in roughly 30 minutes and produces a single discrete GH pulse.
Also known as Mod GRF 1-29 · Modified GRF (1-29) · CJC-1295 no DAC · Sermorelin analogue
At a glance
Dose summary
No regulator and no trial set these numbers. They describe what people actually do, recorded so you can see the range rather than guess at it — which is not the same thing as a recommendation.
Reconstitution
What to draw, at the usual vial
A 2 mg vial reconstituted with 2 mL of bacteriostatic water gives 1.00 mg/mL. A typical 100 mcg dose is 0.100 mL — pull the plunger to 10 units on a U-100 syringe.
Same dose, other vial sizes
| Vial | Water | Concentration | Draw | Units | Doses |
|---|---|---|---|---|---|
| 2 mg | 2 mL | 1.00 mg/mL | 0.100 mL | 10 units | 20 |
| 5 mg | 2 mL | 2.50 mg/mL | 0.040 mL | 4 units | 50 |
| 10 mg | 2 mL | 5.00 mg/mL | 0.020 mL | 2 units | 100 |
The highlighted row is the one quoted above: the smallest listed vial that holds at least four typical doses. Change any of it — a different vial, more or less water, a different dose — on the reconstitution calculator, which draws the syringe to true U-100 graduations.
Mechanism & evidence
What it is, and what is known
Tetra-substituted GHRH (1-29) with no Drug Affinity Complex, so it clears in roughly 30 minutes and produces a single discrete GH pulse. That short half-life is the whole point: it is dosed once to three times daily, typically around 100 mcg (roughly 1-2 mcg/kg, a saturating pulse dose) on an empty stomach, and is paired with a ghrelin agonist such as ipamorelin. It is NOT an approved medicine; the closest approved comparators are sermorelin and tesamorelin.
Consumer supply is research-chemical grade and dosing convention comes from practice, not from a label.
Tolerability
Reported side effects
- Injection site redness, itching or a short-lived welt
- Head rush, flushing or warmth in the minutes after injection
- Mild water retention
- Tingling or numbness in the hands
- Drowsiness when dosed pre-bed
Hard stops
Do not use this if
- Pregnancy, possible pregnancy, or breastfeeding
- Active, suspected or recently treated malignancy
- Under 18
These are flags, not a screening. They do not replace a conversation with a clinician who knows your history.
Handling
Storage
Keep it cold, keep it dark, and label the vial with the date you mixed it. Discard anything cloudy or past the window above.
Combinations
Commonly stacked with
Stacking multiplies the side-effect surface and makes it impossible to tell which compound did what. Add one thing at a time.
Where it shows up
Protocols using this compound
References
Sources
Educational information only, not medical advice. Talk to a licensed clinician before starting, changing, or stopping anything.