Metabolic
AOD-9604
A synthetic fragment of the C-terminus of human growth hormone.
Also known as hGH fragment 176-191 · AOD9604
At a glance
Dose summary
No reliable human half-life has been published for AOD-9604, so none is listed rather than guessed at.
No regulator and no trial set these numbers. They describe what people actually do, recorded so you can see the range rather than guess at it — which is not the same thing as a recommendation.
Reconstitution
What to draw, at the usual vial
A 2 mg vial reconstituted with 2 mL of bacteriostatic water gives 1.00 mg/mL. A typical 300 mcg dose is 0.300 mL — pull the plunger to 30 units on a U-100 syringe.
Same dose, other vial sizes
| Vial | Water | Concentration | Draw | Units | Doses |
|---|---|---|---|---|---|
| 2 mg | 2 mL | 1.00 mg/mL | 0.300 mL | 30 units | 6 |
| 5 mg | 2 mL | 2.50 mg/mL | 0.120 mL | 12 units | 16 |
| 6 mg | 2 mL | 3.00 mg/mL | 0.100 mL | 10 units | 20 |
The highlighted row is the one quoted above: the smallest listed vial that holds at least four typical doses. Change any of it — a different vial, more or less water, a different dose — on the reconstitution calculator, which draws the syringe to true U-100 graduations.
Mechanism & evidence
What it is, and what is known
A synthetic fragment of the C-terminus of human growth hormone. It does not raise IGF-1 or act as a GH secretagogue. Human phase 2 obesity trials used oral doses up to 30 mg daily for 12 weeks and FAILED to beat placebo on weight loss, which is the strongest evidence available and it is negative. There is no dosing consensus for the subcutaneous route: the 250-500 mcg daily range here is a deliberately conservative, narrow band taken from common anecdotal protocols, not from a trial.
Treat any fat-loss or joint claim as unproven.
The caveat
The human phase 2 trial was negative — oral dosing failed to beat placebo on weight loss. That failure is the strongest human evidence this compound has.Tolerability
Reported side effects
- Injection site redness or itching
- Headache
- Generally well tolerated in trials, with an adverse event profile close to placebo
Hard stops
Do not use this if
- Pregnancy, possible pregnancy, or breastfeeding
- Under 18
These are flags, not a screening. They do not replace a conversation with a clinician who knows your history.
Handling
Storage
Keep it cold, keep it dark, and label the vial with the date you mixed it. Discard anything cloudy or past the window above.
Combinations
Commonly stacked with
Stacking multiplies the side-effect surface and makes it impossible to tell which compound did what. Add one thing at a time.
References
Sources
Educational information only, not medical advice. Talk to a licensed clinician before starting, changing, or stopping anything.