Nootropic
Selank
A synthetic heptapeptide analogue of the immune peptide tuftsin, again with a Pro-Gly-Pro tail added for stability.
Also known as TP-7 · Thr-Lys-Pro-Arg-Pro-Gly-Pro · Tuftsin analogue · N-Acetyl Selank Amidate
At a glance
Dose summary
No reliable human half-life has been published for Selank, so none is listed rather than guessed at.
No regulator and no trial set these numbers. They describe what people actually do, recorded so you can see the range rather than guess at it — which is not the same thing as a recommendation.
Reconstitution
What to draw, at the usual vial
A 5 mg vial reconstituted with 2 mL of bacteriostatic water gives 2.50 mg/mL. A typical 300 mcg dose is 0.120 mL — pull the plunger to 12 units on a U-100 syringe.
Same dose, other vial sizes
| Vial | Water | Concentration | Draw | Units | Doses |
|---|---|---|---|---|---|
| 5 mg | 2 mL | 2.50 mg/mL | 0.120 mL | 12 units | 16 |
| 10 mg | 2 mL | 5.00 mg/mL | 0.060 mL | 6 units | 33 |
The highlighted row is the one quoted above: the smallest listed vial that holds at least four typical doses. Change any of it — a different vial, more or less water, a different dose — on the reconstitution calculator, which draws the syringe to true U-100 graduations.
Mechanism & evidence
What it is, and what is known
A synthetic heptapeptide analogue of the immune peptide tuftsin, again with a Pro-Gly-Pro tail added for stability. Its character is anxiolytic rather than stimulant, which is why it is usually paired with, not substituted for, Semax. Like Semax it is a Russian-registered intranasal medicine (commonly a 0.15% solution) and is NOT approved in the US or EU; the human evidence is small Russian trials in generalised anxiety disorder and adjustment disorder, some comparing it against benzodiazepines such as phenazepam, and it has not been independently replicated in Western trials.
Route matters: it is an intranasal drug, not an injectable. Russian clinical dosing runs to roughly 1800-2700 mcg per day divided across two or three administrations; the per-dose range here reflects the more conservative doses typical of non-clinical use rather than the full trial daily total. Plasma half-life is minutes, so no hourly figure is listed. Courses are conventionally short (10-14 days) rather than continuous.
The caveat
Small Russian trials, never independently replicated in Western trials. Registered in Russia only.Tolerability
Reported side effects
- Nasal stinging or irritation at the spray site
- Drowsiness or blunted drive, more likely at the top of the range
- Mild headache
- Bitter taste or post-nasal drip after spraying
Hard stops
Do not use this if
- Pregnancy, possible pregnancy, or breastfeeding
- Under 18
These are flags, not a screening. They do not replace a conversation with a clinician who knows your history.
Handling
Storage
Keep it cold, keep it dark, and label the vial with the date you mixed it. Discard anything cloudy or past the window above.
Combinations
Commonly stacked with
Stacking multiplies the side-effect surface and makes it impossible to tell which compound did what. Add one thing at a time.
Where it shows up
Protocols using this compound
References
Sources
Educational information only, not medical advice. Talk to a licensed clinician before starting, changing, or stopping anything.